Hyperpolarized Imaging

NSF Project CHE-1058727

NSF Project CHE-1363008

We will determine experimentally and understand theoretically the fundamental limits of singlet spin relaxation times in structured materials. This involves synthesis of optimized, next-generation magnetic resonance agents targeted to measure specific metabolic and enzymatic processes and clarify questions on molecular dynamics. The goal here is to use quantum mechanics to design molecules which can preserve hyperpolarization far longer than the few seconds available by traditional methods, thus broadening their utility.